Synthesis Charecterization and biological evaluation of 4-nitro-N-phenyl benzamide and (4-nitrophenyl) (piperidin-1-yl) methanone

*S. Murali Krishna, Y. Padmalatha, L.K. Ravindranath, S. Chandrakala
Department of Chemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India.

A B S T R A C T
Synthesis of mannish bases derivatives containing aromatic rings were synthesized by the condensation 4-nitrobenzoyl azide [2] with mannich bases to form (4-nitrophenyl) (piperidin-1-yl) methanone [3]. In the same way 4-nitrobenzoyl azide [2] treated with substituted aniline to form 4-nitro-N-phenylbenzamide [4]. The purification of these compounds is monitored by T.L.C. The structure of these newly synthesized compounds were characterized by ¹H NMR, ¹³CNMR, Mass, IR, and elemental analysis.
Keywords: Mannich Bases, DMF, Acetone, Substituted Aniline