Saturday , 28 November 2020

Synthesis Charecterization and biological evaluation of 1-(5-(4-aminobenzoyl) -2,2-dimethyl-1,3,4-Oxadiazole-3(2H)-yl)ethanone

 V. Prabhakar1*, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha2, V. Krishna Murthy Naik2
1Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, A.P, India.
2Department of Bio-technology, Sri Krishnadevaraya University College of Engineering & Technology, S.K. University, Anantapuramu–515003, A.P, India

A B S T R A C T
Synthesis of 1,3,4 oxadiazole  derivatives containing aromatic rings were synthesised by the condensation of 4-amino-N-(propan-2-ylidene) benzohydrazide with acetic anhydride. It forms 1-(5-(4-aminobenzoyl)-2, 2-dimethyl-1,3,4-Oxadiazole-3(2H). The structure of these newly synthesized compounds were characterised by 1H NMR, 13C NMR, MASS, IR, elemental analysis.
Keywords: 1,3,4-oxadiazole, TEA, DMF, Hydrazine Hydrate.

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