Thursday , 3 December 2020

Synthesis, Characterization and Antimicrobial Studies of Organosilicon(IV) Complexes Derived from Heterocyclic Sulphonamide Imines

ABOUT AUTHOR 
Sheenam Watts, Nighat Fahmi and R.V. Singh*1 
Department of Chemistry, University of Rajasthan, Jaipur 302004, India

Abstract
This paper deals with the synthesis, spectral, and antimicrobial studies of organosilicon (IV) complexes derived from the interaction of organosilicon(IV) chlorides with the sodium salts of 1-(1-(2-oxo-2H-chromen-3-yl)ethylidene) sulphathiazole in 1:1 and/or1:2 molar ratios and characterized on the basis of analytical, conductance, and spectroscopic techniques. Probable trigonal bipyramidal and octahedral structures for the resulting derivatives have been proposed on the basis of electronic, IR, 1HNMR, and 29Si NMR spectral studies. The free ligand and its metal complexes have been tested in vitro against a number of pathogenic microorganisms in order to assess their antimicrobial properties. Both the ligand and its complexes were found to possess appreciable antifungal and antibacterial properties.
Keywords: Silicon(IV) complexes, Schiff bases, spectral analysis , antimicrobial studies

Scroll To Top