Synthesis and Characterization of Zn-Al-Cl of Hydrotalcites and their Application in Four Component Synthesis of 4H-Pyrano[2,3C] Pyrazoles

Jugraj Jatav*, Ruchi Gupta, Santosh Kumar Bhardwaj
Department of Chemistry, Jiwaji University, 474011 Gwalior, M.P. India

A B S T R A C T
Zn/Al hydrotalcite acts as an efficient heterogeneous basic catalyst for the synthesis of 4H-pyrano[2,3-c] pyrazoles via a multi-component reaction of  hydrazine hydrate, ethyl acetoacetate, aldehydes, and malononitrile in ethanol at ambient temperature. The hydrotalcite catalyst was easily separated from the reaction mixture and can be reused.

Keywords: Heterogeneous catalyst, hydrotalcite, multi-component reactions.