Thursday , 28 March 2024

Synthesis and Characterization of some β-lactam from substituted Malonic Ester

Entesar O. Al- Tamimi* and Hizoom M. Al- Mayiah*
Department of Chemistry, College of Science, Baghdad University, Baghdad, Iraq

A B S T R A C T
Some new compounds were prepared containing β-lactam derivatives from substituted malonic acide with hydrazine hydrate to give hydrazide compounds, then reacted with chloroacetyl chloride in presence of ET3N  to obtain cycle β-lactam. The prepared compounds identyfied by FT-IR spectroscopy, physical propertiesincluding melting point, boiling point and some of them were identified by 1H-NMR, 13C-NMR.
Keywords: FT-IR spectroscopy, β-lactam, ET3N, 1H-NMR, 13C-NMR

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