Dr. Kiran Mishra*
Department of Applied Sciences, Chandigarh Engineering College, CEC, Landran, Mohali-140307, Punjab
A B S T R A C T
2-Aryl-6,7-difluorofenyl-1,3,4-oxadiazolo (3,2-a) (1,3,5)- triazine-5-(6H,7H)- thiones (2a-j) have been orchestrated by the cyclo expansion of para-fluorophenyl 4–fluoro phenyl isothiocynate and 2-(4-fluorobenzylidine ) to (1a-j) 2-amino – 5-phenyl-1,3,4-oxadiazole in dry toluene all the integrated compounds were very much described by their elemental analysis and spectral data. The integrated compounds have been screened for their antifungal action against Phytophthora infestans and Colletotrichum falcatum. Results demonstrated that greatest antifungal activity was appeared by the compounds 2b, 2c, 2g and 2h. These compounds demonstrated 99%, 98%, 99% and 97% hindrance of phytophthora infestants and 97%, 96%, 98% and 97% Colletotrichum falcatum at 1000ppm respectively.
Keywords: Fungitoxicity, oxadiazole, triazine, thiones.