Monday , 29 May 2017

Simple, Convergent Synthesis and Characterization of benzimidazole derivatives (pyrazole linked pyridine): Micro-wave, Sonication and Conventional methods

Dr. Bommera Sammaiah, M. Venkanna, Dr. R. Madhusudhan Raju*
Department of Chemistry, University College of Science, Osmania University, Hyderabad, India.

A B S T R A C T
The preparation of skeleton is an important in the novel drug development. Herein, the skeleton is developed based on anti-ulcerative drugs. A convergent synthesis, approached to simplify the synthesis and succeeded to prepare novel pyrazole-pyridine (benzimidazole) linked derivatives .Finally, coupled both pyrazole and pyridine derivatives by approaching micro-wave, Sonication and conventional techniques. The efficient technology identified as Sonication technique basically time and yield.

Keywords: Antiulcer, Conventional, Convergent synthesis, Micro-wave, Sonication

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