M. Venkanna, Dr. B. Sammaiah, K. Srinuvasulu, Prof. R. Madhusudhan Raju*
Department of Chemistry, Osmania University, Hyderabad-07, Telangana
A B S T R A C T
1,4-Dihydropyridine synthesis has been carried out using Samarium triflet, as a catalyst. This protocol is applicable to a variety of aldehydes with β-ketoester and ammonium acetate to afford the corresponding Hantzsch pyridines in excellent yields. This multi component condensation took placevery smoothly in acetonitrile reflux.
Keywords: Aldehydes, Di ketones, NH4OAc, Samarium triflet, (Sm (OTf)3),1,4-dihydropyridine