Protective effect of withania somnifera on 1, 4-dioxane and trichloro ethylene-induced changes in catalase activity in erythrocytes of in-vitro goat haemic system

ABOUT AUTHOR
Devendra Pratap Singh¹*, Girendra Kumar Gautam¹, Amit Kumar Mishra¹, Poonam Gupta², Ankit Saini^3
1Bhagwant Institute of Pharmacy, Muzaffarnagar, India
²Krishna College of Science and Information Technology, Bijnor, India
³Krishna College of Pharmacy, Bijnor, India

Abstract
Today, numbers of chemicals have been registered for use in the USA and new are being introduced as agricultural chemicals, personal care products, industrial chemicals etc. The atmosphere is being polluted frequently with varieties of chemical substances daily during their manufacture, distribution, use and disposal. The chronic exposure of animals and humans to toxic environmental pollutants is a global health concern. 1,4-dioxane and trichloroethylene are the two of such pollutants which affects can vital functions of human and animal body.  The present study reveals the effects of 1,4-Dioxane and Trichloroethylene on catalase present in erythrocytes and assess the protective effect of Withania somnifera root extract on catalase level and activity of erythrocytes of in-vitro goat haemic system.
Key words: Withania somnifera, 1,4- Dioxane, Trichloroethylene, Catalse