Wednesday , 23 August 2017

Popular Polymers used for Fabricating fast Dissolving Tablets to treat Arthritis: A Technical Review

Yaswanth M, Hindustan Abdul Ahad*, Pruthvimani N, Sashi Kumar, Vanajakshi M, Jacqueline PRB
Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India

A B S T R A C T
A wide range of drugs have been studied in the form of fast dissolving tablets to treat arthritis. Many polymers were tried in single, combination of two and more for fabricating fast dissolving tablets to treat arthritis. An attempt has been made in gathering the information regarding which are the drugs and polymers have been tried in recent years. More than 100 articles published in journals were studied and the polymers combinations used were represented as pie diagrams. The study concludes that 42% fast dissolving tablets were prepared by using microcrystalline sodium. On the other hand the second polymer tried and succeeded was croscarmellose sodium. The 34% fast dissolving tablets were prepared by using croscarmellose sodium with   microcrystalline cellulose were used in combinations of two polymers category. The 22 % fast dissolving tablets were prepared by using croscarmellose sodium with sodium starch glycolate and microcrystalline cellulose was used in combinations of three polymers category.The 55% fast dissolving tablets were prepared by using microcrystalline cellulose with sodium starch glycolate, crosscarmellose sodium and crospovidone were used in combinations of four and above polymers category.
Keywords: Fast dissolving tablets, Arthritis, polymers, survey

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