Sangeetha Sathyanarayan, Dr. P.T. Srinivasan, S. Prasanth
PG and Research Department of Biochemistry, D.G. Vaishnav College, Arumbakkam, Chennai 600106.
A B S T R A C T
The aim of the present study is to look for antioxidant and anti inflammatory activities in the different extracts of Gymnema sylvestre leaves. The preliminary screening of the leaf extracts reveal the presence of phytochemicals like alkaloids, flavanoids, saponins, steroids, glycosides, tannins and phenol in the different extracts. Of the seven extracts studied, ethanol, 40% ethanol and acetone extracts were found to be richest in their phytochemical composition. Antioxidant components like phenols, flavonoids and flavonols are rich in Gymnema extracted with the hydroalcohol (40% ethanol) fraction showing maximum. The 40% ethanolic extract of Gymnema sylvestre exhibited potent antioxidant activity inhibiting DPPH radicals. It also showed the highest total antioxidant capacity. The anti inflammatory potential was evaluated in the aqueous and ethanolic extracts and was found to be appreciable in the ethanolic extracts. The findings confirm the potential benefits of the plant as described in traditional medicine.
Keywords: Gymnema sylvestre, phytochemicals, antioxidant, anti inflammatory.