Thursday , 16 July 2020

New carboxylic α,α-diamino diacid:2-[(Benzoylaminocarboxymethyl)amino] benzoic acid

El Houssine Mabrouk*1 and Abdelilah El Hallaoui2
1Engineering, Electrochemistry, Modelling & Environmental Laboratory (LIEME), Department of Chemistry, Faculty of sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, B.P. 1796, Fez, Morocco.
2Department of Chemistry, Faculty of Sciences and Technics, BP 509 Boutalamine, Errachidia, Moulay Ismail University Meknes, Morocco.

A B S T R A C T
2-[(Benzoylamino carboxymethyl) amino] benzoic acid is a new carboxylic α,α-diamino diacid which was synthesized in very good yield through alkaline hydrolysis reaction of 2-[(1-benzamido-2-methoxy-2-oxoethyl)amino]benzoic acid after obtained this latter through N-alkylation reaction between methyl α-bromo glycinate N-benzoylated and 2-aminobenzoic acid. The structure of the prepared compounds were determined by spectroscopic methods: 1H-NMR, 13C-NMR, and MS data.
Keywords: N-alkylation,α,α-diamino diacid, methyl α-bromo glycinate, alkaline hydrolysis reaction.

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