Department of Pharmaceutical Chemistry, YB Chavan College of pharmacy, Aurangabad, India
Heterocyclic compounds are present in many of our medicines used today. This article gives detailed information on isatine which is one of the versatile heterocyclic molecule. It is a synthetically versatile molecule, a precursor for a large number of pharmacologically active compounds. Isatin and its derivatives have aroused great attention in recent years due to their wide variety of biological and pharmacological activities like antitumor, antimicrobial, anti-inflammatory, anticonvulsant, antiviral, anti HIV, antioxidant, CNS depressant activities. These activities are also possessed by its substituted derivatives as well. The purpose of this review is to provide an overview of the pharmacological activities of isatin and its synthetic and natural derivatives.
Keywords: Isatine, anticonvulsant, antimicrobial, antitumor