Friday , 3 April 2020

Investigation for Nephroprotective Properties of Santalum Album Ethanolic Extracts in Rats

Vijaya Rani1, D.Swamycharan2, Dr. Vijaya Kumar Gampa3
1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.
2Professor, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.
3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.

A B S T R A C T
On the basis of our findings, it may be to suggest that Santalum album has Anti oxidant activity against gentamicin-induced oxidative stress in rats by decreasing the oxidative stress biomarkers Serum creatinine, serum urea in kidneys. Santalum album has Antioxidant Effect, elevated by measuring Anti oxidant enzymes. There is increase in SOD in liver and kidney tissues in gentamicin induced oxidative stress in rats.Santalum album Has high scavenging activity against DPPH Free radicles generating system. Santalum album Has Nephroprotective effect against gentamicin induced toxicity in kidneys by observing the histopathological changes in rat kidney tissues. Santalum album Has many pharmacological activities like anticancer, antimicrobial, anti-inflammatory, analgesic, ant arthritic, antibacterial, anti-HIV, and anthelmintic activities.
Keywords: Santalum album, Nephroprotective, Antioxidant Effect, SOD, Free radicles

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