Tuesday , 29 September 2020

In-vitro and in-vivo antioxidant activity of cordia subcordata whole plant

C. Madhavi Latha*1, K. Bhaskar Reddy2, Hemant Kothari3
1Research Scholar, Pacific University of Higher Education and Research University, Udaipur, Rajastan, India.
2Department of Pharmaceutics, Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor, India.
3Dean, P.G Studies,  Pacific University of Higher Education and Research University, Udaipur, Rajastan, India.

A B S T R A C T
Phytochemical is non nutritive chemical constituent of plants which occur naturally in it termed as phytochemical, or the chemical which is derived from plants are called phytochemical. In Indian system of medicine the whole plant of cordia subcordata Lam, belonging to family Boragenacaeae used for the treatment of various diseases. The objective of the present study was to investigate the antioxidant activity of whole plant of Cordia subcordata. The CCl4 induced erythrocyte damage in rates  models were used to study the in vivo anti oxident  activity and H2O2 free radical scavenging activity and DPPH free radical scavenging activity  model was used to study in-vitro antioxidant activity  of methanol extract of whole plant. Wister strain albino rats with 200mg/kg dose were used for all studies. Ascorbic acid was used as the standard drug.
Keywords: anti oxident, ethanol, erythrocyte damage, free radical scavenging activity, DPPH.

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