aYadav Hanuman Singh*, bGadegone Sunita and cPande Hemant
bDepartment of Chemistry, Kamla Nehru Mahavidyalaya, Nagpur-440009, India
a,cDr. Ira Nimdeokar Research Center for Chemistry, Hislop College, Nagpur 440001, India
A B S T R A C T
One pot synthesis of acid esters by Stobbe condensation of alkylidene / arylidene succinates and aldehydes or ketones, their subsequent hydrolysis to diacidswerereported. The Stobbe condensation of various aromatic aldehydes or ketones with dimethyl succinate gives different types of diacids [2a , (Z)-2-benzylidene-3-(diphenylmethylene) succinicacid)],[2b,(Z)-2- (diphenylmethylene)-3-(1-phenylethylidene) succinic acid], [2c, (E)-2-((4-chlorophenyl)(phenyl)methylene)-3-(diphenyl methylene) succinic acid)], [2d , (2E,3Z)-2-benzylidene-3-(furan-2-ylmethylene) succinic acid)]through green approach. The improved yields of Fulgenic acid were observed by the green approach method as compared with other classical methods employed so far.
Keywords: Green synthesis, Stobbe condensation, aryl aldehydes & ketones and their products.