Friday , 15 December 2017

Formulation and In-Vitro Evaluation of Fentanyl Citrate Sublingual Tablets

Amareshwar Shabada1, Yellanki Prashanthi2
1Assistant Professor, Department of Pharmaceutics, St. Mary’s Pharmacy College, Deshmukhi, Pochampally, Yadadri, Telangana-508284

2Assistant Professor, Department of Pharmaceutical Analysis and Quality Assurance, Nizam Institute of Pharmacy, Deshmukhi, Pochampally, Yadadri, Telangana-508284

Abstract
In the present work, an attempt has been made to develop Sublingual tablets of Fentanyl Citrate. Among all the formulations F4 formulation showed maximum % drug release i.e., 99.16 % in 8 min hence it is considered as optimized formulation. “The F4 formulation contains Cross povidone as super disintegrate in the concentration of 4 mg. 

Keywords: Fentanyl Citrate, Cross povidone, Cross carmellose sodium, Sodium starch, glycollate

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