M. Lalitha1, B. Rajam*2, B. Heeralal3
1Mother Teresa College of Pharmacy, NFC Nagar, Ghatkesar, HYD, Telanagana.
2Assistant Professor, University College of Technology, Osmania University, Hyderabad, Telangana.
3Research Scholar, Department of Pharmacy, University College of Technology, Osmania University, Hyderabad, India.
A B S T R A C T
Diclofenac sodium oral disintegrating tablets were formulated using different concentrations of sodium starch glycolate (superdisintigrant) and other excipients. All the prepared tablets were evaluated for different evaluation parameters. Formulated tablets gave satisfactory results for various evaluation parameters like tablet dimensions, hardness and percent weight variation, percent friability, drug content percentage etc. Formulation containing high concentrations of sodium starch glycolate (super disintegrant) showed excellent drug release pattern. Formulation F1, showed better drug release pattern and released high amount of drug in comparison to the other formulations
Keywords: Diclofenac sodium, sodium starch glycolate, oral disintegrating tablets