Sneha Thakur*, Dr. P. Mani Chandrika, P. Krishnaveni, B. Kalpana, Y. Manisha, K. Lakshmi, E. Lalitha
Bojjam Narasimhulu Pharmacy College for Women, Vinay Nagar, Saidabad, Hyderabad, Telangana, India.
A B S T R A C T
Antibiotics are one of our most important weapons in fighting bacterial infections and have greatly benefited the health-related quality of human life. Natural products have gained popularity as traditional medicine because of its pharmacological activity and low toxicity. The present study was to investigate the poly herbal powder formulation (SRJM-1) for its antimicrobial activity. The peels of fruits of orange, pomegranate, lemon and rhizome of ginger were selected and grinded into coarse powder. The extraction was then carried out using soxhlet apparatus with ethanol as extraction solvent. The extract was concentrated using rotavapour. The poly herbal extract was then formulated into a powder using suitable preservative. The poly herbal formulation (SRJM-1) was screened qualitatively and showed the presence of phenolics, glycosides, alkaloids and flavonoiods. The poly herbal formulation (SRJM-1) was further evaluated for its antimicrobial activity against gram negative Escherichia coli and fungal strain Aspergillus niger and the respective zone of inhibition was calculated. The poly herbal powder formulation (SRJM-1) was found to have antimicrobial activity.
Keywords: Antimicrobial activity, Aspergillus niger, Escherichia coli, poly herbal formulation, zone of inhibition.