Shirish S. Pingale*, Shrikant S. Shewale, Dilip B Satpute
Department of Chemistry, Gramonnati Mandal’s, Arts Com. and Science College Narayangaon, Pune
Abasaheb Garware College, Pune (Affiliated to University of Pune)
Natural products have traditionally provided many of the drugs in use. Despite the achievement of synthetic chemistry and advances towards rational drug design, natural products continue to be essential in providing medicinal compounds and as starting points for development of synthetic analogous. With the increasing power of screening programme and increasing interests in the reservoir of untested natural products, many future drug developments will be based on natural products. Phyllanthus amarus is an annual weed commonly known as bhumi amla in India and is traditionally used to treat flu, dropsy, diabetes, and jaundice. It is also used to treat hepatic and urolitic diseases and have diuretic, antiviral, anticancer, hepatoprotective, antioxidant anti-inflammatory activity. It mainly contains phyllnathin and hypophyllanthin as active ingredients. The aqueous extract of this plant had been employed for treatment of nervous debility, epilepsy, as medhya (intellect promoting) and in vata disorders. In the present study, we reports the proximate survey and phytochemical screening of Phyllanthus amarus. The whole plant material was tested for proximate survey shows 1.96% foreign organic matter, 7.32% ethanol soluble extractives, 17.21% water soluble extractives, 7.22% total ash, 4.68% Acid insoluble ash, 11.38% loss on drying and 2.00% moisture content.
Key words: phytochemicals, proximate analysis, bhumi amla, Phyllanthus amarus