Monday , 27 February 2017

Evaluation of Antioxidant Activity for Salvia Officinalis Using In-Vivo and In-Vitro Methods

Dr. Gampa Vijaya Kumar*1, Dr. Y. Sridhar2, B. Prathyusha3, S. Raju4
1Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.

2,3,4KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.

A B S T R A C T
On the basis of our findings, it may be worthy to suggest that Salvia Officinalis has antioxidant activity against Azathioprine induced oxidative stress in rats by decreasing the oxidative stress biomarkers serum creatinine, serum urea in kidneys.Salvia Officinalis has antioxidant effect, elevated by measuring antioxidant enzymes. There is increase in superoxide dismutase in liver and kidney tissues in Azathioprine induced oxidative stress in rats.Salvia Officinalis has high scavenging activity against DPPH free radical generating system. Salvia Officinalis has nephropretective effect against Azathioprine induced toxicity in kidneys by observing the histopathological changes in rat kidney tissues. Salvia Officinalis has many pharmacological activities like anticancer, antimicrobial, anti-inflammatory, analgesic, antiarthritic, antibacterial, anti-HIV, and antihelmntic activities.

Keywords: Salvia Officinalis, nephropretective, analgesic, antiarthritic, antibacterial, anti-HIV and antihelmntic activities

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