Tuesday , 23 April 2024

Evaluation for Hepatoprotective Activity of Methanolic Extracts of Murraya Koenigii in Mice

Ramidi Ramadevi1, Dr. Y. Sridhar2, Dr. Vijaya Kumar Gampa3
1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.
2Professor, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.
3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.

A B S T R A C T
The present study has been designed to achieve the following aims and objectives. To evaluate the hepatoprotective activity of Murraya koenigii on Azathioprine induced oxidative stress in mice. On the basis of our findings, it may be worthy to suggest that Murraya koenigii has antioxidant activity against Azathioprine induced oxidative stress in mice by decreasing the oxidative stress biomarkers serum AST, serum ALT in liver Murraya koenigii has antioxidant effect, elevated by measuring antioxidant enzymes. There is increase in superoxide dismutase in liver tissue in standard and test extracts treated mice.

Keywords: Murraya koenigii, Azathioprine

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