Sunday , 9 August 2020

Chromatographic and Spectrometric Characterization of Bioactive Compounds from the Leaves of Hyptis lanceolata Poir

About author
Okenwa Uchenna Igwe*
Department of Chemistry, Michael Okpara University of Agriculture,
Umudike,  P.M.B. 7267 Umuahia, Abia State, Nigeria.

Abstract
The ethanolic extract of the leaves of Hyptis lanceolata was subjected to GC-MS analysis. Eight phytochemicals were identified which include imidodicarbonimidic diamide,N,N-dimethyl(5.37%), tetradecanoic acid(3.99%), 3-eicosyne(4.48%), hexadecanoic acid methyl ester(3.44%), hexadecanoic acid ethyl ester(21.87%), 2-hexadecen-1-ol,3,7,11,15-tetramethyl(12.66%), 9,12,15-octadecatrienoic acid, ethyl ester(32.94%) and 9-octadecenoic acid,12-hydroxy(15.24%). The use of Hyptis lanceolata in the treatment of skin diseases and other infections in herbal medicine in Nigeria could be as a result of the synergistic action of these phytochemicals. Also, the underutilization of the plant in phytomedicine was showcased as it could be used in the treatment of diabetes and tuberculosis as a result of its metformin and phytol contents respectively.
Keywords: Hyptis lanceolata, GC-MS, Skin infections, Herbal medicine, Underutilization.

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