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P. Sangamesh*, H. Nagaraju, M. Amzad Khan, Dr. M. Bhavani, Dr. T. Rajavardhan Department of Pharmacy Practice, Balaji College of Pharmacy,Anantapuramu, Andhra Pradesh, India. ABSTRACT Diabetes mellitus is chronic metabolic disorder characterized by hyperglycemia mainly due to inefficient and insufficient supply of insulin hormone. Diabetes is associated with complications such as hypertension, nephropathy, cardio vascular diseases, and retinopathy, neuropathy, which ... Read More »
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Category Archives: Research in Pharmacology and Toxicology studies
Neuroprotective role of Fenoprofen in experimental Parkinson’s disease
Y. Navya Reddya*, Ramya Krishna Pa, K. Rekha Ranib, Kuruva Jyothirmaib, R. Mohana Priyac Dr. M. N. Satish Kumara, T. Spurthid aDepartment of Pharmacology, JSS College of Pharmacy (JSS University, Mysore), Udhagamandalam, Tamilnadu, India -643001 bDepartment of Pharmaceutics, CES College of Pharmacy, NH – 7, Chinnatekur, Kurnool, India – 518218. cDepartmentof Pharmaceutical Chemistry, Dr. K .V Subbareddy Institute of Pharmacy, ... Read More »
Neuroprotective Effect of Walsura Piscidia Implications for Dementia of Alzheimer’s type using Female Albino Wistar Rats
P. Indiramma, B. Kumar* Department of Pharmacology, Ratnam institute of Pharmacy, Pidathapolur, Muthukur, Nellore A B S T R A C T The present study was to evaluate the Anti-dementic effect of walsura piscidia on scopolamine induced female albino wistar rats. Animals were grouped into normal, control, standard, test1 and test2.Except the normal group all the other groups received scopolamine ... Read More »
Evaluation of In-vitro Antioxidant Activity of Ethanolic Extract of Terminalia Arjuna Leaves
B. Aruna1*, R. Venu Madhuri1, Dr. D. Madhuri1, Dr. A.V. Badrinath1, Sk. Karimulla2 1Dr. K.V. Subbareddy Institute of Pharmacy, Dupadu, Kurnool, Andhra Pradesh, India-518218. 2Department of Pharmacology, Narayana Pharmacy College, Chinthareddy Palem, Nellore, Andhra Pradesh-524003 A B S T R A C T Arjuna (Terminalia Arjuna) is a widespread medicinal plant used in the Ayurvedic system of medicine to cure ... Read More »
Neuroprotective Effects of Ethonolic Extract of Aeral parts of Clerodandrum serratum against Bilateral Carotid Artery Occulsion Induced Trasient Gliobal Cerebral Ischemia in Rats
Thanuja*, Sk. Phareeda, Prasanthi.A, K. Srilatha Department of Pharmacology, Ratnam Institution of Pharmacy, Pidathapolur, Muthukur, Nellore, Andhra Pradesh A B S T R A C T Objectives: The objective of this study is to evaluate the neuroprotective effect Global cerebral ischemia was induced by temporary bilateral carotid artery occlusion followed by reperfusion (Oxidative stress). Materials and Methods: Albino wister rats ... Read More »
The safety and efficacy of ADXS11-001 with or without chemotherapy in patients with recurrent cervix cancer who have failed prior cytotoxic treatment
U. Venkatesh1*, Sri Rama Radha1, P. Suresh1, G. Sravan Reddy2 1St John’s College of Pharmacy, Yemmiganur, Kurnool, Andhra Pradesh 2Hi-Q Herbals, Kothapet, Hyderabad, Telangana A B S T R A C T Cervical cancer, cancer in cervix the lower part of the uterus that opens at the top of vagina. It is one of the most fatal diseases that affect ... Read More »
Evaluation of antidiabetic activity of ethanolic extract of Polyalthia Suberosa Roth in alloxon induced diabetic rats.
Saritha Chandra*, M. Divya Sigh, K. Madhu, D. Lakshmi Prasanna, P. Reshma Sai, V. Mary Jagan’s college of Pharmacy, Jangala Kandriga, Nellore, Andhra Pradesh, India A B S T R A C T Polyalthia suberosa Roth species have been extensively used for the management of diabetes in folklore medicine. The current study was designed to investigate the antidiabetic and antihyperlipidemic ... Read More »
Evaluation of Analgesic and Anti-Inflammatory Activity of Citrus Limon Peel in Albino Wistar Rats
Dr. Hareesh Dara*, D Siva Dinesh, Dr. Thatipelli Ravichander St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana, India A B S T R A C T The lemon [Citrus limon (L.) Rutaceae] exhibits many important natural chemical components, including citric acid, ascorbic acid, minerals and phenolic compounds, such flavonoids. Although their biological properties have always been associated with their content ... Read More »
In Vitro Anti-Diabetic and Anti-Arthritic Activity of Hydro Ethanolic Extract of Cynodon Dactylon
K. Jyothsna Jayaraju*, Y. Meenakshi, R. Renuka Devi, P. Sravani, K. Murali Krishna, R. Leela Dr. K.V. Subba Reddy Institute of Pharmacy, Dupadu, Kurnool-518218, Andhra Pradesh, India A B S T R A C T Objective: The present study is aimed to evaluate the in-vitro anti-diabetic and anti-arthritic activity of hydro ethanolic extract of whole plant of Cynodon dactylon. Methods: ... Read More »
Acute and Subacute toxicity study of Guanfacine hydrochloride in Rats by Oral route
U. Venkatesh1*, Sri Rama Radha1, P. Suresh1, G. Sravan Reddy2 1St John’s College of Pharmacy, Yemmiganur, Kurnool, Andhra Pradesh 2Hi-Q Herbals, Kothapet, Hyderabad, Telangana A B S T R A C T Guanfacine is a sympatholytic. It is a selective α2A receptor agonist. These receptors are concentrated heavily in the prefrontal cortex and locus ceruleus. Guanfacine lowers both systolic and ... Read More »
