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Nachiket S. Dighe*, Arun B. Tambe, Santosh S Dengale, Amol S Dighe Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, MS, India-41373 A B S T R A C T There has been considerable interest in the development of novel compounds of some new oxadiazole fused Phenothiazine derivatives containing heterocyclic moiety. Many researchers have synthesized these compounds as ... Read More »
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Category Archives: Pharmaceutical Chemistry and New drug design
Evaluation of Antidiabetic activity of Ethanolic Extract Plant Material (Leaves) Artemisia Vulgaris
G. Sravanthi*1, Dr. G. Nagarjuna Reddy2, Rajani Gunnam3, Dr. J.V. Suresh4, G. Harika 5 1Research Scholar, KLR Pharmacy College, Paloncha, Khammam, Telangana, India 2Professor and Principal, Department of Pharmaceutical Chemistry, KLR Pharmacy College, Paloncha, Khammam, Telangana, India 3Assistant Professor, Department of Pharmacy Practice, KLR Pharmacy College, Paloncha, Khammam, Telangana, India 4Associate Professor, Department of Pharmacology, KLR Pharmacy College, Paloncha, Khammam, ... Read More »
Phytochemical Screening and In vitro Evaluation of Anti-oxidant and Anti-arthritic Activity of Ethanolic Extract of Fruit-Seeds of Lagerstroemia speciosa L. (EE-FSLS)
Asish Bhaumik1, Sanjoy Das*2, Shibu Das3, Soma Acharjee3, Prasenjit Das4 1Department of Pharmaceutical Chemistry, Teja College of Pharmacy, Kodad, Nalgonda, Telangana, Pin-508206, India 2Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, Pin-786004, India 3Department of Pharmaceutical Chemistry, Regional Institute of Pharmaceutical Science and Technology, Agartala, Tripura, Pin-799005, India. 4Department of Pharmacy, Tripura University, Suryamaninagar, Tripura (W), Agartala, Tripura, Pin- 799022, ... Read More »
Synthesis, Characterisation and Antimicrobial Activity of 1-(Morpholin-4-yl)-2-(1,3,4-Oxadiazol-2 Ylsulfanyl)Ethanone Derivatives
M Somashekhar1*, R B Kotnal1, N V Kalyane1 1Department of Pharmaceutical Chemistry, BLDEA’S College of Pharmacy, Vijaypur-586101. A B S T R A C T Considering the biological and chemical relevance of Morpholine derivatives, we have devised novel derivatives of morpholine. The series of morpholine derivatives were synthesized in high yield and quality by reaction of 1-(Morpholin-4-Yl)-2-(1,3,4-Oxadiazol-2 yl-sulfanyl) Ethanone with ... Read More »
Preliminary Phytochemical Investigations of Unifoliate Butea Species: A Member of Fabaceae
J B Devhade* P.G. Department of Chemistry, Jijamata Mahavidyalaya, Buldana, MS, India-443001 A B S T R A C T The present paper attempts to investigate preliminary phytochemical analysis of Unifoliate Butea Species, a member of fabaceae. Plant was reported from Mehkar in Tahsil Mehkar of Buldana district of Maharashtra State. The preliminary phytochemical tests of extracts of Unifoliate Butea ... Read More »
Various Synthesis Methods of 1,3,4-Oxadiazolederivatives: A Review
M Somashekhar*, R B Kotnal Department of Pharmaceutical Chemistry, Bldea’s College of Pharmacy, Vijaypur-586101. A B S T R A C T Heterocyclic molecules such as Oxadiazoles have been synthesized and evaluated for medical and agricultural activities. The disubstituted Oxadiazoles have executed a range of pharmacologic activities. 1,3,4-oxadiazole and 1,2,4-oxadiazole are better known, and more widely studied by researchers Among ... Read More »
Microwave Assisted Synthesis and Antimicrobial activities of 3,4-bis-(4-hydroxy-3-methoxybenzylidene)-7-(N-phenyl)-3,3a,3b,4,5,7-hexahydro-2H-pyrrolo[2,3-c,5,4-c] di pyrazole
Ravindra S. Dhivare1, S. S. Rajput*2 1Department of Chemistry, J.J.T. University, Jhunjhunu, Rajasthan, India 2Department of Chemistry, SVS’s Dadasaheb Rawal College, Dondaicha, Maharashtra, India A B S T R A C T The novel pyrazole derivatives were synthesized by reacting substituted bis-chalcones with 4-hydroxy-3-methoxy benzaldehyde to get 3,4-bis-(4-hydroxy-3-methoxybenzylidene)-7-(N-phenyl)-3,3a,3b,4,5,7-hexahydro -2H-pyrrolo [2,3-c,5,4-c] dipyrazole using solvent-free microwave method. All these derivatives were screened ... Read More »
Synthesis, Characterization and Biological Activity Evaluation of Some 2-(1, 1-Dimethyl Guanidinyl)-4,5-Diaryl Imidazoles
B. Geetha* Pharmacist, Plot No.1, H.No.8-3, SVU Non-Teaching Colony, Opposite Vidyanagar colony, Tirupati-517502 A B S T R A C T A series of 2-(1,1-dimethyl guanidinyl)-4,5-diaryl imidazoles are synthesized by condensing 2-hydroxy -1,2-diaryl ethanones with metformin. All the compounds were characterized and screened for their anthelminthic and anti-tubercular activity. Most of the compounds exhibit both the activities. Keywords: Aromatic aldehydes, ... Read More »
Synthesis and Spectral Studies of Novel 3-(5-mercapto-1, 3, 4-oxadiazol-2-yl)-2H-chromen-2-one Derivatives as Anticancer Agents
Chamandeep Kaur Bhinder1*, Amandeep Kaur2 1Department of Pharmaceutical Chemistry, ASBASJSM COP, Bela, Punjab-140111, India 2Department of Pharmaceutical Chemistry, ASBASJSM COP, Bela, Punjab-140111, India A B S T R A C T In recent years, researchers hunt for a novel anticancer agent mainly from plants. Among various phytochemicals, coumarins have attracted considerable interest in the past few years due to their ... Read More »
The Fruit of Punica granatum act as Potential Cytotoxic agent against the human breast cancer cell line HS-578T
Asish Bhaumik1*, K. Narender Naidu2, Mahendar Boddupally3, Md. Salmasultana4 1, 4Department of Pharmaceutical Chemistry and Analysis, Teja College of Pharmacy, Kodad, Nalgonda-508206, Telangana, India. 2Department of Pharmaceutics, MITS College of Pharmacy, Kodad, Nalgonda-508206, Telangana, India. 3Department of Pharmacology, Pratishta Institute of Pharmaceutical Sciences, Durajpally, Chivemla, Nalgonda-508214, Telangana, India. A B S T R A C T The edible fruit of Punica ... Read More »
