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Chaitramallu M*, Dakshayini C, Devaraju kesagodu Department of Chemistry, University of Mysore, Yuvaraja’s College, Mysore-570006, Karnataka, India. A B S T R A C T The new tetralone (7a‐e) were synthesized as analogues of podophyllotoxin. They were prepared using 1-bromo-3, 4, 5‐trimethoxybenzene and aldehyde derivatives by Grignard reaction which is condensed with diethyl succinate by means of potassium tert-butoxide in ... Read More »
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Category Archives: Pharmaceutical Chemistry and New drug design
Synthesis of Thiazole Derivatives—A Review
Gobala Krishnan P*1, Gnana Prakash K2, Chandra Sekhar K.B3 1Department of Pharmaceutical Chemistry, Vagdevi college of Pharmacy and Research Centre, Brahmadevam, Muthukur, Nellore, Andhra Pradesh, India. 2Department of Pharmaceutics, P Rami Reddy Memorial college of Pharmacy, YSR District, A. P, India. 3Department of Pharmaceutical Chemistry, JNTUA–Oil Technological & Pharmaceutical Research Institute, Anantapuramu, Andhra Pradesh, India. A B S T R ... Read More »
Synthesis, Characterization of New Mercaptobenzoxazole Fused Mannich Bases for Anti-inflammatory and Antibacterial Activity
Kalyani1 G*, Bethi Srinivas2, Sastry3 K.V, Vijaya Kuchana1 K 1Department of Pharmaceutical Chemistry, TKR College of Pharmacy, Hyderabad 2Department of Pharmaceutical Chemistry, Talla Padmavathi college of pharmacy, Warangal. 3Department of Pharmaceutics, Alliance institute of pharmaceutical sciences, Hyderabad. A B S T R A C T Mercaptobenzoxazole is a heteroaromatic chemical compound from the class of Benzoxazoles. A new series of ... Read More »
Antibacterial Activity of 2-(1H-benzo [D]imidazol-2-ylimino)-5-arylidenethiazolidin-4-ones, 1-(1H-benzo[d]imidazol-2-YL)-5-alkyl-3-aryl-1, 3,5-triazinane-2-thiones and 3-(1H-benzo[d]imidazol-2-yl)-5-aryl-1,3,5-oxadiazinane-4-Thiones
Karnaji Harkalaa, Laxminarayana Eppakayala*a, Ramesh Domalab and Thirumala Chary Maringantic* aMahatma Gandhi Institute of Technology, Chaitanya Bharati, Gandipet, Hyderabad, Telangana-500075 bMahatma Gandhi University, Aneparti, Nalgonda, Telangana 508254 cJawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad, Telangana -500 085 A B S T R A C T The antibacterial activity of 2-(1H-benzo[d]imidazol-2-ylimino)-5-arylidenethiazolidin-4-ones, 1-(1H-benzo[d]imidazol-2-yl)-5-alkyl-3-aryl-1,3,5-triazinane-2-thiones and 3-(1H-benzo[d]imidazol-2-yl)-5-aryl-1,3,5-oxadiazinane-4-thiones have been investigated against staphylococcus, Aureus Klebsiella ... Read More »
Synthesis and Anti-Bacterial Activity of Novel Azetidinone Containing Quinoline Derivatives
Mahaboob Basha G*, Pramod. N, Dwarakanadha Reddy P, Swarnalatha D, Nirmala Devi. B, Sarovar Reddy.V Annamacharya College of Pharmacy, Rajampet-516126, Andhra Pradesh, India A B S T R A C T The ultrasonic velocity (u), density (ρ) and viscosity (η) of L-Valine solutions (0.02-0.12 mol.dm-3) in 2% of NaI solutions have been investigated at 288.15, 293.15, 298.15 and 303.15K respectively. ... Read More »
Synthesis and Screening of Anti-inflammatory activity of Coumarins bearing oxy acetic acid moiety
S. A. Tamboli1*, Dr. B. Y. Mane2 1Department of Pharmaceutical Chemistry, Padamshree Dr. Vittalrrao Vikhe Patil Foundation’s College of Pharmacy, Ahmednagar, Maharashtra, India-414 111. 2Asst. prof., Department of Pharmaceutical Chemistry and PG studies, Padamshree Dr. Vittalrrao Vikhe Patil Foundation’s College of Pharmacy, Ahmednagar, Maharashtra, India-414 111. A B S T R A C T Coumarins and its derivatives are considered ... Read More »
Green Synthesis of Silver Nanoparticles: A Review
Prabhakara Rao Dasari*, Prashant Anthony Department of Chemistry, Sam Higginbottom Institute of Agriculture, Technology & Sciences, Allahabad-21100, India A B S T R A C T In the present years, nanotechnology is emerging as a favourite field for research. The nanoparticles have drawn the interest of the researchers from varied fields. These particles find different applications in diverse fields. The ... Read More »
Synthesis and Antimicrobial Evaluation of Some Novel Chalcones and Pyrazoles from Cyclic Imides under microwave irradiation
Prashant P. Chaudhari1 and Shankarsing S. Rajput2* 1DepartmentofChemistry, J.J.T. University, Jhunjhunu, Rajasthan, India 2DepartmentofChemistry, SVS’s Dadasaheb Rawal College, Dondaicha, Maharashtra, India A B S T R A C T A novel class of chalcones and pyrazoles has been prepared by using neutral alumina; under microwave activation and solvent free reaction condition. The compounds were screened for antimicrobial activity against bacterial ... Read More »
Determination of Febuxostat by Complexation with Mercury (Hg II) Ions Using Spectrophotometry
G. Somasekhar*, P. Mamatha, S. Nirosha rani, N. Raja Kumar, S. Ismail Zabiullah, M. Mahaboob Basha Department of Pharmaceutical Chemistry, Safa College of pharmacy, Dupadu, Kurnool, A.P. India A B S T R A C T A simple, sensitive and accurate Colorimetric method was described for the determination of Febuxostat (FBX) an antigout drug. The method is based on yellow coloured ... Read More »
Green Synthesis of Zinc Nanoparticles using Punica granatum Fruit Extract and their Structural and Optical Properties
R. Rajakumari*1, 1S. Kalaiarasi, 2L.Parimala 1PG and Research Department of Physics, Queen Mary’s College (Autonomous), Chennai, Tamil Nadu, India 2Annai Violet College of Arts & Science, Chennai, Tamil Nadu, India A B S T R A C T The Zinc nanoparticles were prepared with the fruit extract of Punica granatum via green synthesis. Though physical and chemical methods are more ... Read More »
