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K.Nithiyananthan1*, K.V.S.Prasadarao2 1Research Scholar, Acharya Nagarjuna University, Guntur, Andhra Pradesh 522510. 2Principal, Rahul Institute of Pharmaceutical Sciences and Research, Chirala, Andhra Pradesh 523157. A B S T R A C T The estimation of Velpatasvir and Sofosbuvir was done by RP-HPLC. The Phosphate buffer was pH 3.0 and the mobile phase was optimized with consists of Methanol: Phosphate buffer mixed ... Read More »
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Category Archives: Analytical Chemistry and New Analytical Methods
Analytical Method Development and Validation For in Vinblastine and Vincristine Combine Dosage Forms by RP–HPLC Method
K.Nithiyananthan1*, K.V.S.Prasadarao2 1Research Scholar, Acharya Nagarjuna University, Guntur, Andhra Pradesh 522510. 2Principal, Rahul Institute of Pharmaceutical Science And Research, Chirala, Andhra Pradesh 523157. A B S T R A C T The chromatographic conditions were successfully developed for the separation of Vinblastine and Vincristine by using XterraC185µm (4.6*250mm) column, flow rate was1ml/min, mobile phase ratio was Phosphate buffer (0.05M) pH4.6: ... Read More »
Development and Validation of Inductively Coupled Plasma Mass Spectrometry Method for Simultaneous Determination of TIN(SN) content in Excipients and Formulations
JagadeswaraRao K1,2, Murali Mohan SV 2and *Rama Rao Malla1 1Department of Biochemistry, Cancer Biology Lab, GIS, GITAM University, Visakhapatnam, India 2Analytical Research and development Department, Shilpa Medicwere Limited, India 3Department of Chemistry, GIS, GITAM University, Visakhapatnam, India A B S T R A C T The pharmaceutical formulation manufacturing process use some of polymers, which contains traces of inorganic elements ... Read More »
Design Formulation and Evaluation of Lansoprazole Mouth Dissolving Tablets
R. Kavitha*, C.S. Pasrameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India-518218 A B S T R A C T The aim of the present work is to investigate the possibility of preparing mouth dissolving tablet containing Lansoprazole by direct compression method. Mouth dissolving tablets are innovative tablet technology where the dosage form ... Read More »
Analytical Method Development and Validation for the Simultaneous Estimation of Tezacaftor and Ivacaftor by RP-HPLC Method
Chitraju Prathyusha, P. Sabiya*, B. Poornima Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupathi, A.P, India. A B S T R A C T The aim of present research work made to develop and validate simultaneous estimation of Tezacaftor and Ivacaftor was done by RP-HPLC. The optimized mobile phase was consists of Acetonitrile: Phosphate buffer pH 2.5 mixed in ... Read More »
Development of new simultaneous RP-HPLC method for the estimation of Dapagliflozin and Saxagliptin in tablet dosage form
M. Kavitha*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr.K.V.Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T The aim of present research work made to develop and validate RP-HPLC method for the simultaneous estimation of Dapagliflozin and Saxagliptin in bulk and combined dosage form. The optimized mobile phase was consists of 0.1% ... Read More »
Simultaneous estimation and validation of Lumacaftor and Ivacaftor in the tablet dosage form using RP-HPLC method
S. Kantha Lakshmi*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T The aim present research work to development and validation of RP-HPLC method for the simultaneous estimation of Lumacaftor and Ivacaftor. Chromatographic separation was evaluated by Phenomenex C18 column (250 X 4.6 mm, ... Read More »
Development of New simultaneous RP-HPLC method for the estimation of Pentazocine HCl and Naloxone HCl in tablet dosage form
M. Sowbhagya Lakshmi*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T The aim of present research work made to develop and validate RP-HPLC method for the simultaneous estimation of Pentazocaine and Naloxone in bulk and combined dosage form. The optimized mobile phase was ... Read More »
Development of new simultaneous RP-HPLC method for the estimation of Glecapravir and Pibrentasvir in tablet dosage form
M. Lakshmi Prasanna*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T The aim present research work to development and validation of RP-HPLC method for the simultaneous estimation of Glecapravir and Piberentasvir. Chromatographic separation was evaluated by Xterra C18 column (250 X 4.6 mm, ... Read More »
Analytical Method Development and Validation for Tranexamic Acid and Ethamsylate in Combine Dosage Form by RP-HPLC
1V. Bhavani*, 2Priyanka K Department of Pharmaceutical Analysis, Smt. Sarojini Ramulamma college of Pharmacy, Sheshadri Nagar, Mahabubnagar, Telangana, India. A B S T R A C T A new method was established for simultaneous estimation of Tranexamic acid and Ethamsylate by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Tranexamic acid and Ethamsylate by using Inertsil ... Read More »
