Thursday , 18 April 2024

Category Archives: Analytical Chemistry and New Analytical Methods

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Analytical Method Development and Validation for Simultaneous Estimation of Cilnidipine and Telmisartan in Combined Tablet Dosage Form by Using RP-HPLC

R. Chandra Sekhar*, Prof. Ravindernath Post graduate student, University College of Technology, Osmania University, Hyderabad, Telangana, India. A B S T R A C T Objective: To develop and validate a suitable method for the simultaneous estimation of Cilnidipine and Telmisartan in Tablet dosage form by using RP-HPLC method. Methods: The chromatographic separation was performed on ZORBAX SB-PHENYL, 250X 4.6mm. ... Read More »

Stability Indicating RP-HPLC Method for the Simultaneous Determination of Anti-Infectious Vials Containing Sulbactam and Ceftazidime in Pharmaceutical Dosage

L Kalyani1 and Chava Venkata N Rao2* 1Department of Chemistry, NRI Institute of Technology, Perecherla, Guntur, Andhra Pradesh 2Department of Chemistry, NRI Institute of Technology, Pothavarappadu, Andhra Pradesh A B S T R A C T A simple, accurate, rapid, and stability-indicating RP-HPLC method for a combination of Sulbactam and Ceftazidime has been developed and subsequently validated in commercial formulation ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Candesartan and Hydrochlorothaizide by RP-HPLC Method Pharmaceutical Dosage Form

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006 Abstract A new method was established for simultaneous estimation of Candesartan cilexitil and Hydrochlorothiazide by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Candesartan cilexitil and Hydrochlorothaizide by using Zodiac sil C18 column (4.6×150mm)5µ, flow rate was 1ml/min, mobile phase ratio was ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Cefadroxil and Ambroxol Hydrochloride by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India Abstract A Simple and rapid stability indicating RP-HPLC method was developed for the simultaneous determination of Cefadroxil and Ambroxol in bulk and pharmaceutical dosage form. A chromatographic separation of the two drugs was achieved with a Symmetry C18 (4.6 × 250 mm, 5 μm partical size, make: Xterra) ... Read More »

RP-HPLC Method Development and Validation for estimation of Metformin, Voglibose, Glimepiride in Bulk and Combined Tablet Dosage Forms

Trupti C. Mahajan*1, Swapnil B. Deshmukh1, Vilas L. Badgujar1, Priyanka N Chhajed1,  Jayshri A. Patil2 1DCS’S A.R.A College of Pharmacy, Nagaon, Dhule 2NES’S Gangamai College of Pharmacy, Nagaon, Dhule A B S T R A C T Background: A simple, sensitive, linear, precise, and accurate method by gradient reversed-phase-high performance liquid chromatography for the simultaneous estimation of metformin (MET), voglibose ... Read More »

A New Validated Stability indicating RP-HPLC Method for the Quantitative Analysis of Phentermine Hydrochloride in Tablet Dosage Form

K.V. Lalitha*1, R. Kiranjyothi2 1Department of Pharmaceutical Analysis, Raghavendra Institute of Pharmaceutical Education and Research, Ananthapuramu – 515001, Andhra Pradesh, India. 2Department of Pharmaceutical Analysis, JNTUA – Oil Technological Research Institute, Ananthapuramu – 515001, Andhra Pradesh, India. A B S T R A C T A novel stability indicating RP-HPLC method was developed for the estimation of Phentermine hydrochloride in ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Atenolol and Nitrendipine by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Gobala Krishnan P*, Munisekhar V, Ranjit Singh B. Rathore Department of Pharmaceutical Chemistry, Vagdevi College of Pharmacy & Research Centre, Nellore, A.P, India A B S T R A C T A new method was established for simultaneous estimation of Atenolol and Nitrendipine by RP-HPLC method.  The chromatographic conditions were successfully developed for the separation of Atenolol and Nitrendipine by ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Fluticasone and Vilanterol by RP-HPLC Method in its Pharmaceutical Dosage Forms

Swapna1, P. Sowjanya1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T A new method was established for simultaneous estimation of fluticasone and vilanterol by RP-HPLC method.  The chromatographicconditionsweresuccessfullydevelopedfortheseparationoffluticasone ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Ivacaftor and Lumacaftor in its Bulk and Pharmaceutical Dosage Forms

Satheesh1, Dr. D. Naresh2, P.Sowjanya3, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T A new method was established for simultaneous estimation of Ivacaftor and Lumacaftor by RP-HPLC method.  ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformine and Gemigliptin by RP-HPLC Method

Nair Ayana Ramesh1, Dr. D. Naresh1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T The estimation of metformin and gemigliptin was done by RP-HPLC. The Phosphate buffer was ... Read More »

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