Wednesday , 20 March 2019

Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Development and Characterization of Gastro Retentive In Situ Gel of ziprasidone Hydrochloride

Uma Rani Gandi1*, R. Nagaraju2 1R.B.V.R.R. Women’s College of Pharmacy, Barkatpura, Hyderabad, Telangana 2Sri Padmavathi Mahila university, Tirupathi. A B S T R A C T The present study aimed at development of Ziprasidone HCl (anti-psychotic agent) into a prolonged release oral dosage form to reduce the frequency of administration which is very difficult for psychic patients. Ziprasidone has poor ... Read More »

Simultaneous determination of Mo(VI) and W(VI) using Second order derivative spectrophotometry

Dr.Srinivas Jagarlapudi*1, Dr.V. Suryanarayana Rao2, A. Ravi Kumar3, Panchumarthi. Srinivas4, CH. Sunil Babu5 Obvez Labs Pvt. Ltd.  Plot No. 22 & 23, ALEAP Industrial Area, Pragathi Nagar, Hyderabad, Telangana-500090, India. A B S T R A C T A simple, selective and sensitive spectrophotometric method has been developed for the simultaneous determination of Molybdenum (VI) and tungsten (VI) using 3,4-dihydroxybenzaldehyde ... Read More »

A Case Report on Zolpidem Induced Nocturnal Sleep Eating Disorder

Ch. Sailaja*1, Y. Karthik Mourya2, R. Pratibha3, Ramesh Dhani4 Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore, Andhra Pradesh, India. A B S T R A C T An adverse reaction is the condition when an unwanted effect caused by the administration of a drug. Here an example of an adverse drug reaction discussed, now a day’s physicians are using zola ... Read More »

A case report on cycloserine induced suicidal tendency in MDR- TB patient

R. Prathibha1, P. Mahesh Kumar*2, Ch. Sailaja3, Ramesh Dhani4 Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore, Andhra Pradesh, India. A B S T R A C T Cycloserine is approved for treatment of MDR-TB with good tolerability in Tuberculosis patients and have various labeled adverse reactions but the neuropsychiatric adverse drug reactions with cycloserine rarely explained. Cycloserine induced psychotic symptoms ... Read More »

Analytical Method Development and Validation of Naloxone and Oxycodone in Bulk and in its Pharmaceutical Dosage Forms Using RP-HPLC as Per ICH guide lines

Dr. G. Uma soundarya1, Bheemanabhoeina Bhargavi2 1Asst. Professor, Nova College of Pharmaceutical  Education & Research, Jupudi Village, Ibrahimpatnam, Krishna, Vijayawada, Andhra Pradesh, India. 2Nova College of Pharmaceutical Education & Research, Jupudi Village, Ibrahimpatnam, Krishna, Vijayawada, Andhra Pradesh, India. A B S T R A C T The proposed HPLC method was found to be simple, specific, precise, accurate, rapid and ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Trimetazidine & Propranolol in Combination by RP-HPLC

Dr. G. Uma soundarya1, Kondapu Ramya2 1Asst. Professor, Nova College of Pharmaceutical  Education & Research, Jupudi Village, Ibrahimpatnam, Krishna, Vijayawada, Andhra Pradesh, India. 2Nova College of Pharmaceutical Education & Research, Jupudi Village, Ibrahimpatnam, Krishna, Vijayawada, Andhra Pradesh, India. A B S T R A C T A new method was established for simultaneous estimation of Trimetazidine and Propranolol by RP-HPLC ... Read More »

Determination of Iodine Value in Triisocetyl Citrate (Citmol-316) by United Satates Pharmacopeia Hanus Method

1Y. Yildiz*, 2M. A. Alfeen, B. Yildiz3 1Science Department, John F. Kennedy Educational Complex, ACT-Academy AP Chemistry Teacher, New Jersey, USA. 2Department of chemistry, Faculty of Second Science PhD, Al-Baath University, Homs, Syria. 3Department of Biomedical Sciences, Rutgers University, Newark, NJ, USA A B S T R A C T The Iodine value (IV) also called “Iodine number or Iodine ... Read More »

Synthesis of the new carboxylic α,α-diamino ester: Methyl 2-benzamido-2-(N-benzyl N-ethylamino) acetate

El Houssine Mabrouk and Abdelilah El Hallaoui Laboratory of Organic Chemistry, Faculty of  Sciences Dhar El  Mahraz, University  Sidi  Mohamed Ben  Abdellah,  B.P. 1796,  Fez,  Morocco A B S T R A C T A simple synthetic approach to racemic methyl 2-benzamido-2-(N-benzyl N-ethylamino) acetate in high yield is reported. This synthesis involves the N-alkylation reaction between methyl α-bromo glycinate or ... Read More »

Synthesis of the new carboxylic α,α-diamino ester: Methyl 2-benzamido-2-(N-benzyl N-methylamino)acetate

El Houssine Mabrouk and Abdelilah El Hallaoui Laboratory of Organic Chemistry, Faculty of  Sciences Dhar El  Mahraz, University  Sidi  Mohamed Ben  Abdellah,  B.P. 1796,  Fez,  Morocco  A B S T R A C T The title compound, Methyl 2-benzamido-2-(N-benzyl N-methylamino) acetate was synthesized in high yield by N-alkylation reaction between methyl α-bromo glycinate or methyl α-azido glycinate N-benzoylated and N-benzyl-N-methylamine ... Read More »

Formulation and Evaluation of Lamivudine Extentended Release Tablets

Dr. Srinivas Jagarlapudi, A. Ravi Kumar*, Panchumarthi Srinivas, M. Raveendra Babu, Alekhya Jagarlapudi Obvez Labs Pvt. Ltd.  Plot No. 22 & 23, ALEAP Industrial Area, Pragathi Nagar, Hyderabad, Telangana. India- 500090. A B S T R A C T Now a day’s, Novel drug delivery system that plays a major role in the delivery of drug to specific site for ... Read More »

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