Monday , 21 January 2019

Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Synthesis, Characterization and Antibacterial Activity of some 1,3- Benzthiazol-2-amine derivatives

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India. Abstract Benzothiazole is an aromatic heterocyclic compounds with the general formula C7H5NS which consists of 5 membered hetero cyclic 1, 3 thiazole ring fused to benzene. Benzothiazole is a simple analogues which play a major  role in research which has wide number of ... Read More »

RP-HPLC Method Development and Validation for Simultaenous Estimation of Montelukast and Fexofenadine Hydrochloride in Bulk and Pharmaceutical Dosage Form

L. Nikhil kumar*1, Chandan R.S2 1JSS Academy of Higher Education and Research, Mysore-570015, Karnataka, India. 2Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysore 570015 Karnataka, India. A B S T R A C T A new method was established for simultaneous estimation of Faxofenadine Hydrochloride Hydrochloride and Montelukast by RP-HPLC method.  The ... Read More »

Stability Indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Pharmaceutical Dosage Form

D. Hemalatha, G. Dharmamoorthy* Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupati-517506, A.P, India ABSTRACT A simple, Accurate, precise method was developed for the simultaneous estimation of the Ledipasvir and Sofosbuvir in bulk and its  Tablet dosage form. Chromatogram was run through Std Kromosil C18 (150 x 4.6 mm, 5m) column. Mobile phase containing Buffer 0.01N KH2PO4: Acetonitrile taken ... Read More »

Simultaneous Estimation Method Development and Validated on Timolol Maleate and Brimonidine Tartrate by Using HPLC

1N. Kalpana Devi*, 2Sindhu Priya Mattepalli, 3D. S.S.N. Neelima 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad Telangana State 3Vikas Institite of Pharmaceutical Sciences – Rajahmundary ABSTRACT A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Timolol Maleate and Brimonidine Tartrate, in its pure form as well as in tablet dosage ... Read More »

Development and Validation of RP HPLC Method for Simultaneous Estimation of Netupitant and Palonosetron in Pharmaceutical Dosage Form

Dr. Gampa Vijay Kumar1*, B. Sravanthi2, N. Gayathri Aparna3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana,India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana,India. A  B  S  T  R A C T On the basis of experimental results, ... Read More »

RP HPLC Method Development and Validation for Simultaneous Estimation of Atzanavir and Ritonavir in Pharmaceutical Dosage Forms

Dr. Gampa Vijay Kumar1*, B.Sravanthi2, K.Indhumathi3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A  B  S  T  R A C T A new method was established for simultaneous ... Read More »

A Stability Indicating RP-HPLC Method Development and Validation for Simultaneous Estimation of Montelukast and Fexofenadine Hydrochloride in Bulk and Pharmaceutical Dosage Form

Dr. Gampa Vijay Kumar1*, Dr. T. Rajesh2, Jaya Chandhra3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A  B  S  T  R A C T A new method was established for simultaneous estimation of Faxofenadine and Montelukast by RP-HPLC method.  The ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Buprenorphine and Naloxone by RP- HPLC Method

Dr. Gampa Vijay Kumar1*, G. Sravanya2 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A  B  S  T  R A C T High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation ... Read More »

Synthesis of diethyl (2-benzoylamino-2-(2-hydroxyethoxy) methyl) phosphonate

El Houssine Mabrouk1*, Khalid Boukallaba1 and Abdelilah El Hallaoui1 1Laboratory of Organic Chemistry, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, Fez, B.P.:1796-Fès Atlas, Morocco ABSTRACT The title compound, diethyl (2-benzoylamino-2-(2-hydroxyethoxy) methyl) phosphonate was synthesized in high yield by O-alkylation reaction between diethyl (2-azido-2-benzoylaminomethyl) phosphonate and ethane-1,2-diol in different solvents in the presence of various bases. The ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Acetaminophen and Tramadol Hydrochloride in Tablet Dosage Form

S. Pavani, V. Hari Baskar*, B. Prathap, Ramesh Dhani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore, A.P, India ABSTRACT A simple, Accurate, rapid and precise method was developed for the simultaneous estimation of the Acetaminophen and Tramadol hydrochloride in Tablet dosage form. The chromatogram was run through. Spurcil, column (4.6 x 150mm, 5µ).Mobile ... Read More »

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