Wednesday , 8 April 2020

Assessment of In-Vitro Antioxidant and Anti Inflammatory activity of Ethanolic Extract of Colocasia Esculenta

Chinni krishnaiah*1, M. Praveen kumar2, D. Swarnalatha3
1Department of Pharmacology, Annamacharya College of Pharmacy, Rajampet, Kadapa Dist. A.P. India.
2Department of Pharmaceutics, Annamacharya College of Pharmacy, Rajampet, Kadapa Dist. A.P. India.
3Department of Pharmacognosy, Annamacharya College of Pharmacy, Rajampet, Kadapa Dist. A.P. India.

A B S T R A C T
Objective:  To assess the in vitro antioxidant and anti-inflammatory activity of the ethanolic extract of colocasia esculenta Methods: In vitro antioxidant activity was evaluated for hydrogen peroxide scavenging assay, nitric oxide scavenging method, reducing power method and thiobarbituric method and in vitro anti-inflammatory activity is also assessed by using inhibition of albumin denaturation method. Results: The ethanolic extract of colocasia esculenta  shown hydrogen peroxide scavenging potential activity is 92.24% at 20µg/ml. The reducing power shows maximum activity shown 81.08% at 100µg/ml and the thio barbituric acid method  shown maximum activity 98.4% at 100µg/ml. Ethanolic extract of Colocasia esculenta showed  95.56% inhibition of denaturation of albumin at 1000µg/ml concentration, while standard diclofenac showed 98.2% inhibition of denaturation of albumin. Conclusion: It can be concluded that ethanolic extract of colocasia esculenta shows good in vitro antioxidant and anti-inflammatory activities.
Keywords: Trapidil, sustained release, Guar gum, karaya gum and xanthan gum

Scroll To Top