Pradeep Kumar Choda1, Namani Srilatha1, Vijaya Kuchana1, D. Yashwanth Kumar2, 1D.S.S.N. Neelima
1Department of Pharmacology, Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana, India
2Scientific and Applied Research Center, Hyderabad, Telangana, India
A B S T R A C T
The effect of Methanolic root extract of Symphytum officinale Linn was investigated in rats to evaluate the anti-ulcer activity by using Aspirin plus pyloric ligation model on experimentally induced gastric ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, PH, free acidity, total acidity and ulcer index. The results indicate that the methanolic extract significantly (P< 0.001) decreases the volume of gastric acid secretion, PH, free acidity, total acidity and ulcer index with respect to control.
Keywords: Symphytum officinale Linn, Anti-ulcer, Anti-secretory