Anti-Inflammatory activity of ethanolic extract of leaves of Mirabilis Jalapa Linn in Albino Wistar rats

P. Sailaja, M. Suchitra, K. Venkata Swapna, M. Abhinaya Priyanka, S. Malavika
Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore-524 346, Andhra Pradesh, India

Abstract
The ethanolic extract of leaves of Mirabilis Jalapa Linn was investigated for anti-inflammatory activity in albino Wistar rats. The ethanolic extract administered by the oral route at a concentration of 200 and 400 mg/kg showed the significant dose dependent anti-inflammatory activity in carrageen in and Formalin-induced paw edema in rats. Anti-inflammatory activity of the tested extract was comparable with that of the standard drug Diclofenac sodium (40 mg/kg). The results lend support to the traditional use of in Mirabilis Jalapa Linn. the treatment of inflammatory diseases.
Key words: Mirabilis Jalapa Linn, ethanolic extract, albino Wistar rats, anti-inflammatory activity.