Thursday , 29 June 2017

Anti-Hyperlipidemic Activities of Modified Diet in Wistar Rats Fed with High at Diet

A. Ravi kumar1*, S. Satyanarayana1, V. Govardhani1, Matle Naga Priyanka2, Gireesh Jampana
1Celon Laboratories Private Limited, Aleap Industrial Estate, Gajularamaram, R.R. Dist, Telgana, India
2Department of Pharmaceutical Analysis Narayana Pharmacy College, Nellore, Andhra Pradesh, India

A B S T R A C T
The aim of the present study was to investigate the evaluate anti hyperlipidaemic activity of modified diet in wistar rats fed with high fat diet. The elevated levels of total cholesterol, phospholipids, triglycerides and low-density lipoprotein due to HFD. Administration of modified diet was significantly (P<0.001) reduced the lipid profile and lipoprotein levels. A significant reduction in HDL-cholesterol was noticed in HFD fed groups (II); however, a significant increased the HDL level was produced by the administration of modified diet. Therefore, it was concluded that modified diet has definite cardio protective effect against hyperlipidaemic.
Keywords: Modified diet, hyperlipidaemic effect, HFD.

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