Kishore Kamere1, Gampa Vijay Kumar1, *S.V. Gopala Krishna2
1Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Keesara, Rangareddy, Telangana, India-501301
2Vasavi Institute of Pharmaceutical Sciences, Vasavi Nagar, Peddapalli, Madhavaram, YSR Kadapa, A.P, India-516247
A B S T R A C T
Recent technological and scientific research has been devoted to the development of rate controlled drug delivery systems to overcome physiological adversities such as short gastric residence times and unpredictable gastric emptying times. The concept behind the development of novel delivery system in certain drawback of conventional dosages form and to overcome the certain aspect related to physicochemical properties of drug molecule and related the formulation development. Controlled release floating drug delivery system is a promising delivery system for a drug candidate having limited absorption window sparingly soluble and insoluble drugs, drugs those locally release in stomach and shows degradability in colon or poor colonic absorption. Floating drug delivery system comes under a gastro-retentive drug delivery system that provides continuous controlled administration of sparingly soluble drugs at the absorption site. This review entitled the detailed scenario related to floating drug delivery system with their advantages over the conventional drug delivery system and also limitation, which are helpful in development of dosages form.
Keywords: physicochemical process, Floating drug delivery system, novel delivery system