B. Kumar*, G. Divya, M. Gobinath
Department of Pharmacy Practice, Ratnam Institute of Pharmacy, Pidthapolur, Nellore, A.P, India
A B S T R A C T
Epilepsy is intermingled with the history of human existence, defined as a brain disorder characterized by an enduring predisposition to generate epileptic seizures and by the neurobiologic, cognitive, psychological, and social consequences of this condition. The brain is involved in nearly every bodily function, including the higher cortical functions. If the affected cortical network is in the visual cortex, the clinical manifestations are visual phenomena. The pathophysiology of focal-onset seizures differs from the mechanisms underlying generalized-onset seizures. Overall, cellular excitability is increased, but the mechanisms of synchronization appear to substantially differ between these 2 types of seizure, Alcohol may cause seizures either by direct intoxication or by withdrawal.
Keywords: Epilepsy, Seizures, brain, Predisposition.