Patel Chirag J1, Satyanand Tyagi2, Patel Kanu J3, Patel Tushar4, Patel Harnish K5,Patel Priyanka H6
1Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020.
2Founder, President & CEO, Tyagi Pharmacy Association, Chattarpur, New Delhi, India-110074.
3Sharda School of Pharmacy, Pethapur, Gandhinagar, Gujarat, India.
4Aditya Bangalore Institute for Pharmacy Education & Research, Bangalore, Karnataka, India.
5 Editor-In-Chief, IJPRBS Journal, Gujarat, India.
6 Director, Research Scholar Hub, Gujarat, India.
Targeting the delivery of drugs has long been a problem for medical researchers – how to get them to the right place in the body and how to control the release of the drug to prevent overdoses. The developments of new and complex molecules called nanosponges have the potential to solve these problems. Nanosponges are tiny sponges with a size of about a virus, which can be filled with a wide variety of drugs. These tiny sponges can circulate around the body until they encounter the specific target site and stick on the surface and begin to release the drug in a controlled and predictable manner. Because the drug can be released at the specific target site instead of circulating throughout the body it will be more effective for a particular given dosage. The most important application of targeted drug delivery system is to treat cancer. The unregulated cell growth and non-specific nature of the treatment makes Cancer difficult to treat by conventional drug delivery system. Hence targeted drug delivery system can be used to treat various cancers like multiple myeloma, breast cancer, prostate cancer, melanoma, lymphoma and other cancers. The objective of the article is to discuss nanosponges with their advantages, method of preparation, characterization, and applications.
Keywords: Nanosponges, Cancer, Polymers, Targeted Drug Delivery