Khaji Mohammad Anees1, Ch. Lalitha2*, Angilicam Avinash3, Dr. M. Sreenivasulu4
1B.Pharm 4th Year, Narayana Pharmacy College, Chinthareddy Palem, Nellore, A.P, India.
2Assistant Professor, Dept. of Pharmaceutical Chemistry, Narayana Pharmacy College, Nellore, A. P, India.
3Assistant Professor, Dept. of Pharmaceutics, Narayana Pharmacy College, Nellore, A. P, India.
4Principal, Narayana Pharmacy College, Chinthareddypalem, Nellore, Andhra Pradesh, India.
A B S T R A C T
Nanobiotechnology is a recently coined term describing the junction of the two existing but isolated worlds of engineering and molecular biology. It is a combination of three words: “nano” tiny, “bio” is living things, and “technology” is about tools. It refers to the ability to create and manipulate biological and biochemical materials, devices, and systems at atomic and molecular levels. Thus, it is an integration of physical sciences, molecular engineering, biology, chemistry, and biotechnology, and holds considerable promise of advances in pharmaceuticals and health care. Nanotechnology helps in improving the drug solubility and bioavailability by enhancing the drug release, the formulation quality, decreasing toxicity, and efficient targeted therapy. Nanomaterials are at the leading edge of the rapidly developing field of nanotechnology. In this review we discussed the role of nanobiotechnology in molecular diagnosis, drug discovery, and development of nanomedicine and personalized medicine. The FDA approval is essential for clinical applications of nanotechnology and substantial regulatory problems could be encountered in the approval of nanotechnology-based products therefore we also discussed about the limitations of use of nanobiotechnology in drug discovery.
Keywords: Quantum dots, Nanoparticles, Nanopores, Nanoshells, Nanotechnology, Nanotubes